Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and a-Amino Acids
نویسنده
چکیده
Background The catalysis of reactions with organic molecules void of transition metals has lately assumed a prominent role in asymmetric synthesis. Among different catalysts, proline, an abundant, inexpensive amino acid available in both enantiomeric forms, has emerged as arguably the most practical and versatile. The simultaneous presence of a carboxylic acid and amine bestows a unique bifunctional character to this chiral molecule.
منابع مشابه
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تاریخ انتشار 2003